Differences Between Jefferson and Hamilton Schools Essay - 3

Differences Between Jefferson and Hamilton Schools - Essay Example This notion is supported by the explanation that elites have more resources and better skills set for the formation and execution of government. This view is further disregarded by Jefferson through another counter-argument that every form of government is corruptible and giving such power to limited individuals makes rest of the public vulnerable. Hamilton, on the other hand, believes that for stronger control over a system, executives in the government need to be strong and have complete sovereignty (Geer et al. 13). Another fundamental difference between Jefferson and Hamiltonian approaches is the presence of state government. Jefferson believes that the division of power between state and national governments would allow citizens to have more control of government’s decisions whereas Hamilton recognizes the concept of strong national government. Other than supporting citizens’ extensive rights, Jefferson believes that expanding gateways of influence would allow bett er liberty to people and will keep government accountable for its actions. This view is also contested by Hamiltonian approach as it believes that restriction in gateways would allow access of only educated, skilled and experienced elites to the government matters. Jeffersonian view believes that state should be more involved in internal matters instead of global issues. A hamiltonian approach, on the contrary, believes that strong strategic positioning in global affairs through established industrial and military power would benefit United States (Cunningham 106). Analyzing these differences helps in understanding that a Hamiltonian approach provides a more holistic system of government. It is understandable that all the individuals i.e. elites and common men, cannot have the same profile and skills for participating in government. Therefore, allowing educated individuals to have access to government offices ensures that only the most suitable and capable talent runs this instituti on. Of course, selecting elites representing different social segments would benefit American citizens more. There are rather limited benefits accrued to the American nation due to irreconcilable differences among these two approaches. Now, United States has a system which allows elites to represent interests of communities and states. Both of these regimes have strong disagreements regarding structure and role of government. Perhaps, finding a middle way i.e. system run by elites for the welfare of Commons would be more suitable. Question No. 6 Division of Power in American Constitution Division in power represents a division of authority among different branches of government along with national and state governments. The federal government divides into legislature which is Congress, executives which include president and other bureaucracy, and judiciary which is Supreme Court and federal courts (Geer et al. 11). Another name for this vertical division of power is the separation o f powers. This division of power among different branches of government ensures that no branch becomes too independent and strong in its authority and operations that it harms the interests of common citizens. This system of branches having authority over each other is called checks and balance.  

How Indian Cinema Evolved over the Years Essay Example for Free

How Indian Cinema Evolved over the Years Essay A hundred years ago on this date, India’s first film Raja Harishchandra was released. Over the past hundred years, our cinema and its facets have evolved and how!! The hero From mooch to macho From a bulky mustached Raj Kapoor in the 40s to a six-pack flaunting, butt-baring John Abraham now, the Bollywood hero has had quite a makeover. The 50s was the era of method-acting with the likes of Dilip Kumar, while in the 60s, Rajesh Khanna and Dev Anand epitomised romance on screen. After Khanna’s guru kurtas and fluffy hairtop, Amitabh Bachchan brought the angry young man into the picture in the 70s and 80s with Zanjeer, Deewar and Agneepath, also bringing to the fore, bell bottoms and side burns. The 90s was the time of the lover boys Shah Rukh Khan, Aamir Khan and Salman Khan dancing in exotic foreign locales. Now, the Bollywood hero is not restricted by genre or style and fits into every mould. He is a looker, chocolatey, experimental and total paisa vasool, read Ranbir Kapoor and Imran Khan. The heroine From feeble to fabulous In the early decades, the heroine in Indian cinema had only one objective in life, that of being a sati-savitri, who never looked beyond her family and husband. The kitchen was her cocoon, and she epitomised all things good. Through the 1940s, 50s and 60s, heroines such as Mala Sinha, Meena Kumari, Madhubala, Nanda and Asha Parekh ruled these roles. It was only in the 80s and 90s that she evolved as a strong character (Rekha in Khoon Bhari Mang, 1988), (Meenakshi Sheshadri in Damini, 1993). While in the early 2000s, she was still the demure girl, she managed to live her life on her terms like Rani Mukerji in Kabhie Alvida Naa Kehna. And the heroine today is the sexy, uber cool woman who cares for little more than her own life. Way to go girl! The villain From scary to suave From the usual lot of wicked village zamindars, smugglers, murderers, rapists, dacoits and terrorists, the larger-than-life Bollywood villains have become rare in new age cinema. Thus the traditional villain, Loin, Shakal, Mogambo, Dr Dang and Badman, has died a natural death. The wigged, cigar-smoking avatars played by the likes of Pran, Prem Chopra, Amrish Puri, have made way for smart and sometimes more-adorable-than-the-hero kind of villains. Exhibit A- Saif Ali Khan (Omkara) and Shah Rukh Khan (Don). No lines are drawn now and black characters have became grey with lead actors playing antagonists in films, almost replacing the dedicated villains. This marked the end of ever reverberating iconic one liners like â€Å"Kitne aadmi the?† and â€Å"Saara sheher mujhe Loin ke naam se jaanta hain.† The maa Rona-dhona to supercool From the God fearing and homely mum to a party freak, mothers in Bollywood have come a long way since 1930s. While Nargis in Mother India (1957) played a mother who went through hardships and struggled to bring up her offsprings, Nirupa Roy in the 70s became synonymous with white saris and a melancholic look. Then came Reema Lagoo, with her bindi and sindoor, an ideal middle class Indian mother in Qayamat Se Qayamat Tak (1988) and Maine Pyar Kiya (1989), who tried to be a friend to her son. But now, mothers are the uber cool women who are ready to accept even same-sex couples, case in point, Kirron Kher in Dostana (2008). And now there are mom who drink and dance at weddings, ala Dolly Walia in Vicky Donor (2012). The item girl Taboo to must-haves The dancing girl evolved from the Cabaret seductress, the free-spirited banjaran, the sensuous courtesan to dancing temptresses in half-saris. In the 40s and 50s, Cuckoo Moray, hotted up the screen with her innocent charm. The 50s saw Vyjayanthimala woo the audience in songs such as Chad Gayo Papi Bichua in Madhumati (1958) in ghagra cholis, and junk silver jewellery. Helen ruled the 60s and 70s, emerging in a bold avatar with dramatic ensembles. The 80s saw the trend of heroines appear in item numbers with Zeenat Aman in Qurbani (1980). Madhuri Dixit’s Choli Ke Peeche Kya Hai became the ultimate tease in the 90s. The item girls of 2000s are sexy, not afraid to show skin and love to play hard to get, be it Malaika Arora Khan in a mid-riff baring choli dancing atop a train or Katrina in Sheila Ki Jawani. The comedian Funny face to frontman The comedian in the 40s, was the fat man with funny facial expressions, whose mere presence made audiences laugh. In the 1950s, the lean Johnny Walker broke that trend and managed to win hearts with his slapstick humour. Kishore Kumar, essentially a singer, redefined comedy by using his songs like Meri Pyari Bindu (Padosan 1968) as elements of fun in films. But it was Mehmood, with his fringed hair and impeccable dialogue delivery who became the king of comedy in the 1970s. The next big thing in comedy was Johnny Lever, who left audiences in splits with his body language and dialogues in films like Raja Hindustani (1996) and Dulhe Raja (1998). Now, it’s the heroes — Akshay Kumar (Hera Pheri), Ajay Devgn (Golmaal) who are doubling as comedians. The friend Sidekick to the right-hand man The side kick or hero’s best friend, every Bollywood film has had one. The role could be that of a fun buddy who provides comic relief to the film or that one jigari dost who stays with the hero through thick and thin (in other words, fights for the hero and often dies in the end). From the days of Mukri and Mehmood, who played the hero’s good friend in the 1950s and 60s to the current time where actors like Arshad Warsi and Sharman Joshi play as powerful characters as the hero himself, this portrayal has had a sea change. Mehmood in Humjoli (1970), for instance, played a sidekick who brought the house down with his antics, but Arshad Warsi in the Munnabhai series (2003/06) played the ideal Robin to Sanjay Dutt’s Batman, and got some of the best lines in the films. The romance Touch-me-not to pre-marital sex Romance in Bollywood turned from bold to coy and back to racy and bold. The silent film, ‘A Throw of Dice’ (1929) saw actor Seeta Devi kiss actor Charu Roy. Post-independence, in the 1940s, romance became conservative. The Cinematograph Act in 1952, called kissing on screen indecent and romance became associated with clasping hand and staring into each other’s eyes. Kissing was shown with two flowers coming together or honey bees sucking nectar from flowers. 1970s was Raj Kapoor’s era that brought a passion back to romance with movies such as Bobby (1973), Satyam Shivam Sundaram (1978). It was the 90s that romance took a pure and sweet form the two blockbuster hits Hum Aapke Hain Kaun (1994) Dilwale Duhaniya Le Jayenge (1995). Now, in the 2000s, pre-marital sex shown in films like Salaam Namaste (2005) and Rockstar (2011), is considered cool. The music Melodies to racy tracks The 1930 and 40s, were defined by nasal renditions by the likes of KL Saigal (Jab Dil Hi Tooth Gaya, Shahjahan, 1946) and Noorjehan. The 50s were all about soul-soothing melodies. Songs like it Pyaar Huya Ekraar Huya (Shree 420 1952) or Jaane Woh Kaise Log The (Pyaasa 1957) became epics. However, it was R D Burman, who single-handedly changed the course of Bollywood film music, and introduced westernised tunes in songs in the 60s. While 70s remained the decade of a mix of soft and fast numbers, the 80s turned Bollywood music on its head, as Bappi Lahiri brought in disco music. Disco Dancer (1982) marked the beginning of a range of high-on-noise, low-on-lyrics songs. The 1990s churned out several hugely forgettable numbers, except for musical hits like 1942 a Love Story (1994), Saajan (1991). The 2000s have been the decade of experimenting thus Sonu Nigam and Yo Yo Honey Singh both find place in the same film. The dialogues Melodrama to quirky Power-packed dialogues get the maximum seetis from the audience, and why not. A film is often remembered for its iconic dialogues. Kaun kambakth bardasht karne ke liye peeta hai, from Devdas that’s a favourite even with the ‘daarubaaz’ of today. However, dialogues like Kitne aadmi the, and â€Å"Kuttey main tera khoon pi jaunga† from Sholay, â€Å"Pushpa, I hate tears† from Amar Prem and â€Å"Mere paas maa hai† from Deewar; have gone on to become epic. In the 1990s, heroes impressed their lady love with dialogues. Thus came, â€Å"I love you Kkk Kiran† (Darr), â€Å"Bade bade shehron mein aisi chhoti chhoti baatein hoti rehti hain.† (DDLJ 1995). In 2000, quirky dialogues such as, Main apni favourite hoon (Jab We Met), Picture Abhi Baki Hai Dost (Om Shanti Om) are the big hits among film buffs.

Standardization of Anti-diabetic Poly Herbal Formulation

Standardization of Anti-diabetic Poly Herbal Formulation 1. Introduction Now-a-days most of developed as well as developing countries use Ayurvedic medicines then they uses it in past. They avoid use of allopathic drugs because of high risk of adverse effects. So, for the sake of community it is important to standardize the dosage form available in market. Standardization of formulation is evidence that the formulation contains constituents which it says to be contained. In present work formulation containing Gymnemic acid and Resveratrol has been studied. This formulation is anti-diabetic. Gymnemic Acid (GYM) is major constituent isolated from leaves of plant Gymnema Sylvester belonging to family Asclepiadacea. (1) Plant has a property of masking the sugar test so it is known as â€Å"GURMAR†. Gymnemic acid is a triterpenoid saponin found in the leaves of Gymnema Sylvester. (2) Many studies have shown that oral administration of Gymnema extract reduces serum glucose level and improves glucose tolerance in mildly diabetic rats. (3) Administration of water extract of Gymnema sylvestre leaves was found to increase serum insulin level suggesting its insulin releasing effect. (4) Number of beta cells within pancreatic tissue were increased which suggests a restorative effect of the Gymnema extract on pancreatic tissue. (5) So, from above it is now known that Gymnemic acid has the ability to decrease blood glucose level in diabetic patient which ultimately relives Diabetes. Resveratrol (RES) (3,4†²,5-trihydroxy-trans-stilbene) is polyphenolic constituent isolated from plant Polygonum Cuspidatum belonging to family Polygnaceae. (6) It has been reported that Resveratrol has a variety of biological and pharmacological effects including antioxidant, anti-inflammatory, antiplatelet, anticarcinogenic effects, modulation of lipid metabolism and cardioprotection. (7) In pancreatic ÃŽ ²-cells, insulin secretion is linked to the oscillations in membrane potential, intracellular Ca2+ and metabolism. The variations in the ATP/ADP ratio control the conductance of ATP-dependent K+ channels leading to depolarization and periodic influx of Ca2+. The resultant membrane depolarization activates voltage dependent L-type Ca2+ channels and triggers intracellular Ca2+ release, elevating intracellular Ca2+ both in the cytosolic compartment and within the mitochondria, and thereby initiating insulin secretion. (8) From the survey of various literatures it is found that Gymnemic acid has been estimated by various analytical techniques like HPTLC, HPLC Gravimetery. (9) While Resveratrol had been estimated by HPLC and spectrometric techniques. (10) Not a single method is reported for the estimation of both constituents simultaneously. Present work has been focused on estimation of both constituents simultaneously. Here estimation of both constituents was done by UV-Visible spectrometry and HPTLC. For estimation of both constituents simultaneously UV-visible Spectrophotometric and HPTLC methods were developed and validated. Figure 1: Gymnemic acid Table 1: Gymnemic acid Group Figure 2: Resveratrol 2. Experimental Chemical Reagents Gymnemic acid relative Standard was extracted from the formulation. This relative standard was compared with standard obtained from Clearsynth TM Private Ltd (Andheri (w), Mumbai, India) . Then the prepared relative standard was used for methods. Same way, Resveratrol was extracted from formulation and then compared with standard Sigma-Aldrich constituent. Marketed formulation here used was Resveratrol plus (with Gymnemic acid) {Zenith Nutrition’s} containing 100mg Resveratrol and 500 mg Gymnemic acid per 2 capsules. All reagents for UV-Visible Spectrophotometry and HPTLC are Methanol, Chloroform, Ethanol, Glacial Acetic Acid, water and Benzoyl Chloride. Methanol, Chloroform and Ethanol used were analytical grade purchased from merk solutions. Triple distill water was made in laboratory by distillation assembly. Benzoyl Chloride was purchased from SD fines Chemicals. Instruments UV-Visible Spectrophotometric was developed on a Shimadzu UV-Vis double beam spectrophotometer, model 2400 PC series, with spectral width of 1 nm, wavelength accuracy of 0.5nm and a pair of 10 mm matched quartz cells (Shimadzu , Japan). The HPTLC instrumentation consisted of a Linomat V sample applicator with 100  µL Hamilton syringe and a TLC III scanner controlled by WinCATS software (Camag, Muttenz, Switzerland) Merck TLC plates coated with 60F254 silica gel on aluminum sheets were used as stationary phase. The plates were developed in a Camag 10 x 10 cm twin through chamber that was previously saturated for 20 minutes with mobile phase. Spectrometric Conditions GYM didn’t contain chromophore in structure so it has to be derivatized for UV-Visible detection. Benzoyl Chloride was used as derivatizing agent. The solutions of GYM RES were scanned in the spectrum mode from 200 to 400 nm, and from that 303nm for Gymnemic acid determination, 318.4 nm for Resveratrol determination and 349 nm for isoabsorptive point for Q ratio method were selected for simultaneous estimation. Chromatography Condition The solutions were spotted in the form of hands of 5 mm width on pre-coated silica gel 60F254 aluminum plates using a Camag 100  µL sample applicator syringe. They were activated at 110 oC in an oven for 20 minutes before sample application. A constant application rate 0.1 µL/s was applied and bandwidth was 9 mm between two bands. Spotted plates were developed in twin through chamber which is previously saturated for 20 minutes with mobile phase containing Chloroform: Methanol: Glacial acetic acid (13: 4: 0.5 %). The plates were developed for 8 cm run length. The plates were dried by hair dryer and then post derivatization done by dipping plates in Vanillin-Sulphuric acid solution. Then it is heated in hot air oven at 105oC for 5 minutes. Then plates were scanned at 575nm in TLC III scanner. Preparation of solutions Preparation of Standard solution for UV Resveratrol relative standard 10 mg was accurately weighed which is transferred to 10 ml clean volumetric flask. This much quantity was dissolved in 10 ml of ethanol to produce 1000 µg/ ml standard stock solution. From standard stock solution 1 ml is transferred to another 10 ml of volumetric flask and volume was made up with methanol to produce 100  µg/ ml working standard stock solution. Gymnemic acid relative standard 100 mg was accurately weighed which is transferred to 10 ml clean volumetric flask. This much quantity was dissolved in 10 ml of triple distill water to produce 10000  µg/ ml standard stock solution. From standard stock solution 1 ml was transferred to 10 ml volumetric flask diluted with methanol to produce 1000  µg/ ml working standard solution. Benzoyl chloride was diluted in ethanol first and then in methanol lastly to produce 125  µg/ ml solution which was used as derivatizing solution. Preparation of sample solution for UV 10 capsule’s shells were removed and powders from those capsules were mixed and from that weight equivalent to 10 mg Resveratrol and 50 mg Gymnemic acid was weighed accurately and transferred to 10 ml of volumetric flask volume made up with mixture of ethanol: water (1:1). From this solution 1 ml solution was taken diluted with mixture of ethanol: water (1:1).this solution is working sample solution further dilution done by the same mixture. Preparation of standard solution for HPTLC Resveratrol relative standard 20 mg and Gymnemic acid relative standard 100 mg was accurately weighed and transferred to two different 10 ml volumetric flask respectively in which weighed quantity was dissolved in 10 ml ethanol : water (1:1) mixture to produce RES 2000  µg/ ml and GYM 10000  µg/ ml standard stock solution. From these solution 5 ml solution was transferred to 10 ml volumetric flask diluted with ethanol: water (1:1) up to 10 ml to produce RES 1000  µg/ ml and GYM 5000  µg/ ml working standard stock solution. Preparation of sample solution for HPTLC 10 capsule’s shells were removed and powders from those capsules were mixed from that weight equivalent to 20 mg RES and 100 mg Gym was weighed. That much amount of powder was accurately transferred to 10 ml volumetric flask and dissolved in ethanol: water (1:1) mixture. From this solution 5 ml was taken and filtered with 0.45  µm filter sized syringe filter. This solution was then diluted with mixture of ethanol: water (1:1) up to 10 ml solution to produce RES 1000  µg/ ml equivalent and GYM 5000  µg/ ml equivalent. Assay method validation Preparation of calibration curve For UV-visible Spectrophotometric method individual solutions were prepared in methanol from working standard stock solution to produce 5-25  µg/ ml RES and 25- 125  µg/ ml GYM solution. Benzoyl chloride 10  µL was added to each solution. Then these solutions were analyzed in methanol at three different wavelengths at 303 nm, 318.4 nm and 349 nm. Calibration curve here made up was absorbance v/s concentration. For HPTLC method different aliquots of were taken from standard stock solution to make final concentration of RES 1000  µg/ ml and GYM 5000  µg/ ml in the same solution. Then different aliquots were spotted on activated TLC plate. The concentration of RES was varied between (5-25)  µg/ spot while for GYM it was (25-125)  µg/ spot. Then plate was developed in mobile phase and was developed to scan as mention above at 575 nm. Calibration curve here made was peak area v/s concentration of constituents. Accuracy (recovery) For UV-visible spectrophotometer solution of standard RES was added to previously analyzed sample solution at three different levels (80%, 100 % and 120%). Same procedure been followed to have a GYM accuracy by adding standard stock solution at three different levels (80%, 100 % and 120%). Amount of standard RES added was (8, 10 and 12  µg/ ml) to 10  µg/ ml sample solution. Amount of standard GYM added was (40, 50 and 60  µg/ ml) to 50  µg/ ml sample solution. For HPTLC known amount standard solution of RES (8, 10 12  µg/ ml) and GYM (40, 50 60  µg/ ml) added to previously analyzed sample solution having concentration of RES 10  µg/ spot and GYM 50  µg/ spot. Precision The intra-day and inter-day precision of proposed methods were determined by estimating corresponding responses three times on the same day and on three different days for three different concentrations. For UV-Visible spectroscopy RES concentrations were 8, 10 and 12  µg/ ml measured at wavelengths 318.4 nm and 349 nm.GYM concentrations were 45, 50 and 60  µg/ ml measured at wavelengths 303 nm and 349 nm. For HPTLC three different dilutions were made having both RES and GYM in those solutions ranging (RES 9, 10 and 12.5  µg/spot) and GYM (45, 50 and 62.5  µg/ spot). For repeatability in HPTLC, sample solution containing 10  µg/spot RES and 50  µg/ spot GYM was measured in terms of response. LOD LOQ The sensitivity of analytical method was evaluated by determining LOD and LOQ. They are measured by following equations: LOD: 3.3 à ¯Ã‚ Ã‚ ³/ S LOQ: 10 à ¯Ã‚ Ã‚ ³Ãƒ ¯Ã¢â€š ¬Ã‚ ¯Ãƒ ¯Ã¢â€š ¬Ã‚  S Here, à ¯Ã‚ Ã‚ ³ is standard deviation of intercept and S is slope in linearity equation. Specificity For HPTLC spots were scanned for its purity with standard sample and checked whether they give a same response or not. This was done by spectral scanning in WinCats HPTLC. Robustness The robustness of methods was studied by analyzing the same samples of RES and GYM with deliberate change in parameters. The changes in responses were noted. For HPTLC, spots scanned at ( ± 2 nm) and mobile phase ratio change was performed. For UV-Visible method solutions were scanned at ( ± 2 nm). 3. Results and Discussions Simultaneous estimation of RES and GYM was difficult task because they are isolated from herbal source and they have RES: GYM ratio 1:5 in marketed formulations. System suitability parameters System suitability run for HPTLC was performed before each validation run. Five replicate spots were made. Parameters monitored were Rf value and Peak areas of them. (Table 2) Table 2: System suitability Parameters HPTLC Optimization of Method For HPTLC Various experimental conditions such as the mobile phase and the wavelength of detection were optimized to achieve accurate, precise and reproducible results for the estimation of RES and GYM. Good resolution and sharp peaks with minimum tailing of these drugs (Rf RES 0.78, Rf GYM 0.236) was obtained by using mobile phase Chloroform: Methanol : Glacial acetic acid (13: 4 :0.5%) at wavelength of detection 575 nm. Figure 3 : optimized Chromatogram of HPTLC, RES (10  µg/spot) GYM ( 50  µg/spot) Figure 4: Wavelength selection for HPTLC of RES and GYM For UV-Visible Spectrophotometric Form overlain spectra (Figure 5) of methanolic solution of RES and GYM three wavelengths were finalized for analysis 303 nm, 318.4 nm and 349 nm. The method here used for simultaneous estimation is Q ratio method. Here both of constituents are measured at 349 nm isoabsorptive point and 303 nm and 318.4 nm GYM and RES respectively. Figure 5: wavelength selection after derivatization of GYM, BCL (Benzoyl Chloride) and RES Method validation of proposed methods Optimized methods were validated in compliance with ICH guidelines. The results of various parameters are discussed following: Linearity For UV Spectrophotometric method, linear correlation was obtained between absorbance and concentration for RES 5-25  µg/ ml at 318.4 nm 349 nm and GYM 25-125  µg/ ml 303 nm 349nm.( Table 3) For HPTLC method, linear correlations were obtained between peak area and concentration of RES was 5-25  µg/spot and GYM was 25- 125 µg/spot. (Table 4) Accuracy The percentage recovery values of RES and Gym were obtained in the range of 98% to 103 %, and relative standard deviation values for both constituents in two methods were less then 2%, it shows that methods are accurate for both constituents. Values are shown in table 3 and 4. Precision Inter-day and intra-day variation in quantification of RES and GYM showed that RSD values were always less than 2% during the analysis by both methods. These low RSD values show that methods are precise. Values of precision studies for UV spectrometry and HPTLC are in table 3 and 4 respectively. LOD and LOQ For UV-Visible spectrometry method LOD and LOQ for RES was found to be 0.09 µg/ml and 0.28 µg/ml respectively. LOD and LOQ for GYM were 0.63 µg/ml and 1.92 µg/ml respectively. For HPTLC method LOD and LOQ for RES were 0.065  µg/spot and 0.20  µg/ spot respectively. LOD and LOQ for GYM were 1.2  µg/spot and 3.87  µg/spot respectively. Specificity For HPTLC method, a good correlation was obtained between standard and sample spectra of RES and GYM correlation suggests that there in no interference in quantification of RES and GYM. Robustness Robustness of the methods was studied by performing assays of RES and GYM in capsule formulation. The parameters are deliberately altered and changes were recorded. Assay values were calculated in the changed parameters. Methods proved to be robust, because assay values in changed parameters were within limits. Assay of marketed formulation Assay of Resveratrol plus from ZENITH nutrition was performed in both the methods. Results of assay were compared with corresponding amounts claimed on capsule. The assay results are shown in table 3 4. Table 3: UV-Visible method Validation parameters Table 4: HPTLC Validation Parameters Conclusion Developed HPTLC and UV-Visible Spectrophotometric method was found to be simple, accurate, precise, rapid, sensitive and robust for the estimation of RES and GYM in combined dosage form. The validation data and recovery shows that methods are free from inferences of excipients used in formulations. Thus method is useful for both constituents to be estimated by both methods. References x

Fear in Lord of the Flies Essays -- Lord of the Flies William Golding

Fear in Lord of the Flies In the novel the Lord of the Flies, written by William Golding, fear is the cause of all of the problems that take place on the island. At first, the island is thought to be splendid and a paradise, but as the boys' stay on the island increases, so, too, do their fears. The boys soon become afraid of each other and soon after that the boys break up and fight because of the fear. The boys' original fears are of what they think are beasts. "Then people started getting frightened" (Golding, 88). This was spoken by Ralph at an assembly because he knew that things were breaking up and he also knew why. It was the fear. In the novel the Lord of the Flies, fear is the root of the trouble that is caused on the island. The boys' fear turns into fear of each other after only a short time on the island. Many of the boys leave Ralph and join Jack's tribe of hunters because Jack provides them with fun. Jack's tribe goes hunting and has feasts and everyone, even if it is only for a short time, forgets about the beast and ignores it. After a while, though, some of the boys are in Jack's tribe because of their fear, but not their fear of the beast. They stay in Jack's group because they are afraid of Jack and, eventually, Roger. Jack controls them all by showing he is merciless; He's going to beat Wilfred. What for? Robert shook his head doubtfully. I don't know. He didn't say. He got angry and made us tie Wilfred up (176). Jack beats up members of his tribe for no reason at all, except to instill upon them the fear of himself. Soon, everyone is afraid of Roger also. The twins are forced to join Jack's tribe and are terrified of Roger. "You don't know Roger. He's a terror." "-and t... ...ic, see a beast sitting on top of the mountain and Ralph, Jack and Roger confirm what the twins saw, there is complete fear. No one is willing to walk alone or even to go deep into the forests, except for Simon. The boys are terrified and this is when things start to break up. Now, the fear moves on from what they think is the beast to something much more dangerous. Now, they are afraid of each other. At first the island is thought to be a paradise by the boys. It is a dream come true. The boys are living every child's fantasy. Then things start to go horribly wrong. Fear sets in. In this novel, William Golding illustrates that fear is everywhere and can wreak havoc on many things. In this case the boys become afraid of each other and for all of them survival becomes impossible. They eventually they realize that dreams can easily turn into nightmares.

Learning Preferences Essay

Describe your strongest dimension on the personality spectrum. My strongest dimension on the personality spectrum is a giver (32). Every word on the list of giver describes me. My honesty is probably one my strongest. As I get older and being the mother of two terrific boys, I just feel at this exact moment in my life there is no need to lie. Honesty is the key, but sometimes I feel I am a little too honest and may hurt someone’s feelings, but not intentionally. I just feel â€Å"it is what it is†. I love promoting peace whether it’s a world issue or family. I just think that everyone would be a lot happier in their lives if we can be honest with one another and promote positivity. I hate drama. 2. Describe how each practice activity reinforced or contradicted something about yourself. In the Personality Spectrum Assessment it contradicted me on being a visual learner. In the Multiple Pathways to Learning Assessment it resulted in me being under-developed, but in one of the activities in the Personality Spectrum it said that I was fine in this area. I must say it left me a little baffled, but at the same time I feel my answers can vary to certain situations that can me contradict myself in this case. I feel that I can adapt to different learning environments quite well, just like I’m learning the OLS. This is definitely an contradiction. The Barsch Learning Style Inventory activity made me realize that I am more proficient in the kinesthetic learning style than I am a visual learner. This activity made me think hard and deep about what my learning abilities are and what I thought they were. I definitely love working hands on and encouraging others. I am usually the one that normally starts dishing out ideas first when I am grouped up with others. .

Critical Evaluation of Romeo and Juliet By Baz Luhrmann Essay Example

Critical Evaluation of Romeo and Juliet By Baz Luhrmann Essay Example Critical Evaluation of Romeo and Juliet By Baz Luhrmann Paper Critical Evaluation of Romeo and Juliet By Baz Luhrmann Paper Essay Topic: Romeo and Juliet Romeo and Juliet directed by Baz Luhrmann is possibly the most famous love story of all time about the two star crossed lovers Romeo and Juliet. Luhrmann had the task of remaking the classic play, written by the even more famous William Shakespeare, into a film that would appeal to a younger audience despite the Shakespearian language. Due to the language in the film, Luhrmann has to use many different techniques to help the audience understand what is happening or to help them relate to the story. The film is set in a fictitious city that is meant to be Verona in Italy but it looks more like a larger American city. This helps younger viewers relate to the film as many of them will live in large cities themselves. The most basic way of Luhrmann showing how different the Montagues and Capulets were was their race. The Montagues are white Americans and the Capulets are Hispanic, from a southern American country. This immediately tells the audience that the families are different and that racism may play a large part in the story. Also, he shows the families are different by the way they dress, the Montagues dress like surfers, very casually with shorts and shirts with bright colours where as the Capulets dress formally wearing smart trousers and shirts with blank blazers. Although the families have their distinctive dress senses Romeo and Juliet both dress differently. When the audience first sees Romeo he is not dressed in beachwear, he is dressed formally. This shows that he is not like the rest of his family. Juliet also dresses differently; she is always seen in white to signify her pure and angelic form. She changes from white to black later on in the film, this is when she realises she is alone and she isnt like her family even if she wants to be. Her family disown her when she expresses her distress at the thought of having to marry Paris as she secretly loves Romeo. Another even more important way that Luhrmann shows Juliet is different is that she is white while her family are Hispanic. Another way Luhrmann gets round the difficult language of the film is by his use of casting. The two family leaders Lord Capulet and Lord Montague, played by Paul Sorvino and Brian Dennehy respectively have played many roles as gangsters. This gives the audience the right impression of them, nasty and unfriendly characters. Luhrmann also recruited Leonardo Di-Caprio, voted The Most Handsome Peron on the Planet who had a huge fan base before Romeo and Juliet so many of his young female fans would go to see the film just to see him. It would also make the film more enjoyable for them. Claire Danes was chosen to play the part of Juliet because she is pretty but not glamorous and this would make girls think that they dont have to be perfect to find a boyfriend. She had also never had a major role in a film before so this would mean she would not bring any past roles into the film which would damage her credibility as the angelic Juliet. Luhrmann made some questionable decisions whilst making Romeo and Juliet like setting it in modern times and keeping the Shakespearian language, another was choosing to introduce drugs into the film. Romeo takes an ecstasy tablet before the party but he sincerely regretted it after as it ruined his party. He took the ecstasy because Mercutio gave him it and through a mix of peer pressure and not wanting to offend Mercutio he takes the drug. Luhrmann is critical and makes a bad impression of them in the hope that some people will be deterred by the way Romeos party is ruined by drugs. Drugs is a major issue in modern days so this is yet another way in which some of the audience can relate to the film as some people may have had experiences with drugs and need to deal with them. Luhrmanns use of the music in the film is very helpful for people who cant understand the language of the film. The film starts with a lot of action and confrontations so the music is frantic and sounds like western cowboy-showdown music. By contrast, the first time the audience meets Romeo the music is very calm and soothing to show Romeo is very mellow and not looking for trouble or fights. The music also helps people know if something bad is going to happen. For example when Romeo and Juliet marry the music is happy and merry but for the next scene it changes to very deep and dramatic music, this is just before Mercutio is killed. When Romeo and Juliet realise they can never be the music changes to sad music. Some people may not have caught on to what was happening without the music but it changes effectively to show they can never be together. In conclusion, Luhrmanns techniques of producing a Romeo and Juliet film that appeals to a young audience were somewhat successful. Although the Shakespearian language is very difficult to understand at times young viewers still watch and enjoy the film.

French Words with New Meanings in English

French Words with New Meanings in English French Words with New Meanings in English French Words with New Meanings in English By Mark Nichol Thanks to the Norman Conquest, and to the long dominance of France in European culture and politics, almost half the words and phrases in the English lexicon (including that of its American variety) are derived from French. The list below consists of words used in American English that acquired one or more senses distinct from that or those of the French words from which they are descended. After each term, the American English meaning(s) is/are listed, followed in parentheses by the French meaning(s). 1. accoutrement: accompanying items or accessories (a ludicrous costume or tasteless attire) 2. aprà ¨s-ski: socializing after skiing (snow boots) 3. auteur: a film director or other artist who artistically dominates a creative endeavor (an author) 4. au naturel: naked (acting or looking natural, unaltered or unadulterated) 5. bà ªte noire: someone or something avoided or disliked out of fear (someone or something hated) 6. boutique: a shop selling designer or distinctive clothing, or, as an adjective, describing a small, exclusive business (a shop) 7. boutonnià ¨re: a flower placed in a buttonhole (a buttonhole) 8. chef: a professional cook (a boss) 9. claque: a group of admirers (a group of theatergoers paid either to applaud or to criticize a performance) 10. corsage: flowers worn on a woman’s dress or around her wrist (a woman’s chest, and attire covering this area) 11. coup: a forced change of government (a hit) 12. coup de main: surprise attack (give a hand) 13. debut: a first performance by an artist or entertainer (a beginning) 14. dà ©colletage: a low neckline, cleavage (lowering a neckline, or, in agricultural and technical contexts, cutting) 15. en masse: a group or mass moving as one entity (a collection or crowd) 16. entrà ©e: an entrance, or the main course of a meal (an entrance, or appetizers preceding a meal or before the main course) 17. à ©pà ©e: a specific fencing sword (a sword) 18. exposà ©: published material pertaining to a fraud or scandal (a report or talk) 19. hors d’oeuvre: a snack (the first course of a meal) 20. outrà ©: unusual (exaggerated or extravagant, or outraged) 21. prà ©cis: a summary (accurate, precise; also, an abridged textbook) 22. premiere: a first performance or presentation (first) 23. recherchà ©: obscure, pretentious (sophisticated, studied) 24. rendezvous: a clandestine meeting, or a location for an appointed meeting or reunion or a joining of two spacecraft (an appointment, date, or meeting) 25. reprise: a repetition of a piece of music during a performance (an alternate version or cover version, or rebroadcast) 26. rà ©sumà ©: an employment history with a list of qualifications (a summary) 27. risquà ©: sexually provocative (risky) 28. seance: a gathering to communicate with spirits (a meeting or session) 29. touchà ©: acknowledgment of a point made, or of a hit in fencing (emotionally touched) 30. vignette: a brief description or scene (a small picture) Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Vocabulary category, check our popular posts, or choose a related post below:100 Exquisite AdjectivesRunning Amok or Running Amuck?Practice or Practise?